SYT Oncology FISH

TEST: 510384
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CPT: Contact CPT coding department at 800-222-7566, ext 6-8400.
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Synonyms

  • FISH
  • Leukemia FISH
  • Lymphoma FISH

Special Instructions

There will be an additional charge for processing paraffin block samples or for samples that require culture.

Expected Turnaround Time

5 - 7 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Information

Related Documents

Specimen Requirements

Specimen

Fixed-cell pellet from a cytogenetic analysis, slides with metaphases and/or interphase nuclei, or bone marrow touch prep slides. Blood, bone marrow, cerebrospinal fluid (CSF), FNA, paraffin block are also acceptable with additional charge.

Volume

Fixed-cell pellet, three slides, 10 mL blood (adult), 5 mL blood (pediatric), or 3 mL bone marrow

Minimum Volume

Fixed-cell pellet from a cytogenetic analysis, two slides, 5 mL blood (adult), 1 mL blood (pediatric), or 1 mL bone marrow

Container

Green-top (sodium heparin) tube; pediatric Vacutainer® is optimal or lavender-top (EDTA) tube

Collection

Transport to the testing lab at room temperature; use a cool pack or LabCorp transport kit. Do not allow sample to freeze.

Storage Instructions

Maintain specimen at room temperature.

Causes for Rejection

Broken or dirty slides; excessive cellular debris or stained slides; decalcified bone cores; frozen specimen

Test Details

Use

Confirmation/identification of leukemia/lymphoma-related alterations; leukemia/lymphoma monitoring of residual disease, transplants, and indolent clones (see list or call lab for probe availability)

Methodology

Fluorescence in situ hybridization (FISH)

Additional Information

SYT gene rearrangement is most often linked with a t(X;18) chromosome translocation commonly associated with synovial sarcoma.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
510384 SYT Oncology FISH 510260 Specimen Type 31208-2
510384 SYT Oncology FISH 510261 Cells Counted N/A
510384 SYT Oncology FISH 510265 Cells Analyzed N/A
510384 SYT Oncology FISH 510382 FISH Result 48674-6
510384 SYT Oncology FISH 510268 Interpretation 50398-7
510384 SYT Oncology FISH 510383 Director Review: 48672-0

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The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf