RET Oncology FISH

TEST: 510315
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CPT: Contact CPT coding department at 800-222-7566, ext 6-8400.
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Synonyms

  • Adenocarcinoma
  • Non−Small-cell Lung Cancer

Expected Turnaround Time

5 - 7 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Information

Specimen Requirements

Specimen

FNA; formalin-fixed paraffin-embedded blocks are acceptable.

Volume

Five slides (4- to 5-micron thick sections)

Minimum Volume

Two slides (4- to 5-micron thick sections)

Container

Paraffin block

Storage Instructions

Maintain specimen at room temperature.

Causes for Rejection

Broken or dirty slides; excessive cellular debris or stained slides; decalcified bone cores; absence of tumor or quantity not sufficient for analysis

Test Details

Use

Confirmation/identification of cancer-related alterations in non−small-cell lung cancer

Limitations

This test was developed, and its performance characteristics determined, by LabCorp. It has not been cleared or approved by the US Food and Drug Administration (FDA).

Methodology

Fluorescence in situ hybridization (FISH)

References

Takeuchi K, Soda M, Togashi Y, et al. RET, ROS1 and ALK fusions in lung cancer. Nat Med. 2012 Feb 12; 18(3):378-381.

LOINC® Map

Order Code Order Code Name Order Loinc Result Code Result Code Name UofM Result LOINC
510315 RET Oncology FISH 510893 Specimen Type 31208-2
510315 RET Oncology FISH 510894 Cells Counted 62361-1
510315 RET Oncology FISH 510895 Cells Analyzed 62360-3
510315 RET Oncology FISH 510896 FISH Result 48674-6
510315 RET Oncology FISH 510316 Interpretation 62365-2
510315 RET Oncology FISH 510317 Director Review 48672-0

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