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RB1 Oncology FISH
CPT:
Contact CPT coding department at 800-222-7566, ext 6-8400.
Synonyms
- Leukemia FISH
- Lymphoma FISH
Expected Turnaround Time
3 - 5 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Information
Specimen Requirements
Specimen
Fixed-cell pellet from a cytogenetic analysis, slides with metaphases and/or interphase nuclei, or bone marrow touch prep slides. Blood, bone marrow, cerebrospinal fluid (CSF), FNA are also acceptable.
Volume
Fixed-cell pellet, three slides, 10 mL blood (adult), 5 mL blood (pediatric), or 3 mL bone marrow
Minimum Volume
Fixed-cell pellet from a cytogenetic analysis, two slides, 5 mL blood (adult), 1 mL blood (pediatric), or 1 mL bone marrow
Container
Green-top (sodium heparin) tube; pediatric Vacutainer® is optimal or lavender-top (EDTA) tube
Collection
Transport to the testing lab at room temperature; use a cool pack or LabCorp transport kit. Do not allow sample to freeze.
Storage Instructions
Maintain specimen at room temperature.
Causes for Rejection
Broken or dirty slides; excessive cellular debris or stained slides; decalcified bone cores; frozen specimen
Test Details
Use
Confirmation/identification of leukemia/lymphoma-related alterations; leukemia/lymphoma monitoring of residual disease, transplants, and indolent clones (see list or call lab for probe availability)
Methodology
Fluorescence in situ hybridization (FISH)
Additional Information
Unique sequence DNA probe for deletion of the retinoblastoma (RB-1) gene region.
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 510374 | RB1 Oncology FISH | 510240 | Specimen Type | 31208-2 | ||
| 510374 | RB1 Oncology FISH | 510241 | Cells Counted | N/A | ||
| 510374 | RB1 Oncology FISH | 510244 | Cells Analyzed | N/A | ||
| 510374 | RB1 Oncology FISH | 510373 | FISH Result | 48674-6 | ||
| 510374 | RB1 Oncology FISH | 510246 | Interpretation | 50398-7 | ||
| 510374 | RB1 Oncology FISH | 510372 | Director Review: | 48672-0 |
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CPT Statement/Profile Statement
The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf