<span>PV</span>
July 15, 2019

PV

The importance of pharmacovigilance (PV) as a science, critical to both effective patient care in clinical practice and public health is growing. **Disclaimer: This article was previously published. Sciformix is now a Covance company.
<span>The path to PV automation: Past, present and future</span>
July 18, 2019

The path to PV automation: Past, present and future

Explore the current state of PV automation in light of the challenges being faced by the industry and the PV automation landscape, as well as Covance's recent innovations in automation and the how these solutions have benefited our sponsors.

<span>NarlaAACC19-FCAL.pdf</span>
August 4, 2019

NarlaAACC19-FCAL.pdf

AACC 2019 -- Calprotectin is a calcium-heterodimer protein which is abundant in the cytoplasm of neutrophils. This is a biomarker with good sensitivity and specificity in case of inflammatory Bowel disease (IBD) which is a chronic inflammatory gut.
<span>WagnerAACC19.pdf</span>
August 4, 2019

WagnerAACC19.pdf

AACC 2019 -- Symmetric and asymmetric dimethylarginine (SDMA and ADMA) are metabolites of the post-translational modification of arginine residues in histones. SDMA is produced by all body tissues and is cleared almost exclusively by the kidneys, making it an attractive biomarker for the evaluation of renal function.
<span>Kim-KincaidAACC19.pdf</span>
August 4, 2019

Kim-KincaidAACC19.pdf

AACC 2019 -- Hepatotoxicity is an ongoing focus for drug development. Drug-induced liver injury (DILI) figures prominently in the termination of candidates for new drug applications to the FDA and other regulatory authorities.
<span>NarlaAACC19-Troponin.pdf</span>
August 4, 2019

NarlaAACC19-Troponin.pdf

AACC 2019 -- The requirements from IFCC (International Federation of Clinical Chemistry) to qualify a cardiac Troponin assay to be qualified as a high sensitive assay are that the, Assay must have analytical imprecision of 10% at the 99th percentile, Assay must be able to measure cTn above the LOD in >50% of the patients and the 99th percentile should b