CML FISH Reflex to JAK2V617F Mutation Analysis, Quantitative, With Reflex to CALR Mutation Analysis, JAK2 Exon 12-15 Mutation Analysis and MPL Mutation Analysis by NGS

TEST: 512221
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CPT: Contact CPT coding department at 800-222-7566, ext. 6-8400. 
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Special Instructions

Please direct any questions regarding this test to oncology customer service at 800-345-4363. If reflex test is performed, additional charges/CPT code(s) may apply.

Expected Turnaround Time

3 - 5 days

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Related Information

Specimen Requirements

Specimen

Bone marrow or peripheral blood

Volume

Bone marrow: 2 mL in pediatric green-top (heparin) tube; peripheral blood: 3 mL in pediatric green-top (heparin) tube

Container

Pediatric green-top (heparin) tube

Collection

Submit at room temperature using Leukemia/Lymphoma Specimen Transport Kit (supplied by Labcorp). Specimens should arrive in the laboratory within 48 hours of collection. Indicate date and time of collection on the test request form.

Storage Instructions

Maintain specimen at room temperature.

Test Details

Use

This test is used to confirm the diagnosis of CML, establish the chronic phase karyotype for comparison with blast crisis alterations and monitor residual disease.

Limitations

This test was developed and its performance characteristics determined by Labcorp. It has not been cleared or approved by the Food and Drug Administration.

Methodology

Cytogenetics; fluorescence in situ hybridization (FISH)

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