Poster - 14 April 2023 3D reconstructed pancreas: A model capturing the unique tumor microenvironment and stromal architecture of pancreatic cancer Read Moreabout 3D reconstructed pancreas: A model capturing the unique tumor microenvironment and stromal architecture of pancreatic cancer
Poster - 14 April 2023 Inhibition of murine myeloid suppressor cells increases CD8+ T cell activation in vitro Read Moreabout Inhibition of murine myeloid suppressor cells increases CD8+ T cell activation in vitro
Poster - 14 April 2023 A novel technique to preclinically assess the ability of targeted therapies to inhibit both primary and metastatic non-small cell lung carcinoma Read Moreabout A novel technique to preclinically assess the ability of targeted therapies to inhibit both primary and metastatic non-small cell lung carcinoma
Poster - 14 April 2023 Differential immunomodulation following checkpoint blockade in the orthotopic ID8-luc ovarian model Read Moreabout Differential immunomodulation following checkpoint blockade in the orthotopic ID8-luc ovarian model
Poster - 14 April 2023 Preclinical assessment of chimeric antigen receptor (CAR) T persistence and functionality in the disseminated NALM6-Luc human B cell acute lymphoblastic leukemia (ALL) model Read Moreabout Preclinical assessment of chimeric antigen receptor (CAR) T persistence and functionality in the disseminated NALM6-Luc human B cell acute lymphoblastic leukemia (ALL) model
Poster - 14 April 2023 Transcriptional analysis of TME in MC38 colon carcinoma model following checkpoint inhibition Read Moreabout Transcriptional analysis of TME in MC38 colon carcinoma model following checkpoint inhibition
Poster - 14 April 2023 Fractionated dosing: A more clinically relevant approach to radiotherapy in preclinical tumor models Read Moreabout Fractionated dosing: A more clinically relevant approach to radiotherapy in preclinical tumor models
Poster - 14 April 2023 Growth kinetics and immune cell profiling of BT-474 human breast carcinoma and Raji-Luc human Burkitt's lymphoma in four strains of triple immunodeficient mice Read Moreabout Growth kinetics and immune cell profiling of BT-474 human breast carcinoma and Raji-Luc human Burkitt's lymphoma in four strains of triple immunodeficient mice
Poster - 13 September 2022 Spontaneous Neoplasms in the Uterus, Vagina and Cervix of Rats from 104-Week Carcinogenicity Studies Read Moreabout Spontaneous Neoplasms in the Uterus, Vagina and Cervix of Rats from 104-Week Carcinogenicity Studies
Poster - 13 September 2022 Spontaneous Neoplasms in the Uterus, Vagina and Cervix of Mice from Carcinogenicity Studies Read Moreabout Spontaneous Neoplasms in the Uterus, Vagina and Cervix of Mice from Carcinogenicity Studies
Poster - 12 September 2022 Comprehensive analysis of the association between RAS mutation and immune checkpoint marker expression Read Moreabout Comprehensive analysis of the association between RAS mutation and immune checkpoint marker expression
Poster - 16 May 2022 In Vitro Characterization of CD19 CAR T Cells Derived by Electroporation of mRNA Read Moreabout In Vitro Characterization of CD19 CAR T Cells Derived by Electroporation of mRNA
Poster - 16 May 2022 Development of an In Vitro Assay for Assessment of IL-2 Independent CAR T Proliferation Read Moreabout Development of an In Vitro Assay for Assessment of IL-2 Independent CAR T Proliferation
Poster - 8 April 2022 Comprehensive Cell- and Gene-Based Tumor Profiling Using Flow Cytometry and NanoString in a Murine Bladder Cancer Model Read Moreabout Comprehensive Cell- and Gene-Based Tumor Profiling Using Flow Cytometry and NanoString in a Murine Bladder Cancer Model
Poster - 8 April 2022 Systematic Evaluation of Cloudman S91 and YUMM1.7 Murine Melanoma Models to Immunotherapy and Focal Radiation Read Moreabout Systematic Evaluation of Cloudman S91 and YUMM1.7 Murine Melanoma Models to Immunotherapy and Focal Radiation
Poster - 8 April 2022 Model Characterization and Tumor Immune Profile Assessment for Syngeneic RM-1 Murine Prostate Cancer in Male C57BL/6 Mice Read Moreabout Model Characterization and Tumor Immune Profile Assessment for Syngeneic RM-1 Murine Prostate Cancer in Male C57BL/6 Mice
Poster - 8 April 2022 Reconstructed Plate-Based 3D Screening Assays That Predict In Vivo Responses Read Moreabout Reconstructed Plate-Based 3D Screening Assays That Predict In Vivo Responses
Poster - 8 April 2022 Chimeric Antigen Receptor (CAR) T Cell Generation for Therapeutic Testing in the Disseminated NALM6-Luc Human B-Cell Acute Lymphoblastic Leukemia Model Read Moreabout Chimeric Antigen Receptor (CAR) T Cell Generation for Therapeutic Testing in the Disseminated NALM6-Luc Human B-Cell Acute Lymphoblastic Leukemia Model
Poster - 7 December 2021 Combined Focal Radiation and Anti-mCTLA-4 Antibody Therapy Modulates Myeloid Subset Phospho-STAT3 Levels in the 4T1 Tumor Microenvironment, and Results in Tumor Growth Inhibition Read Moreabout Combined Focal Radiation and Anti-mCTLA-4 Antibody Therapy Modulates Myeloid Subset Phospho-STAT3 Levels in the 4T1 Tumor Microenvironment, and Results in Tumor Growth Inhibition
Poster - 10 November 2021 Cancer Testis Antigen Burden: A Novel Predictive Biomarker for Immunotherapy in Solid Tumors Read Moreabout Cancer Testis Antigen Burden: A Novel Predictive Biomarker for Immunotherapy in Solid Tumors
Poster - 10 November 2021 Prevalence of Secondary Immunotherapeutic Targets in the Absence of Established Immune Biomarkers in Solid Tumors Read Moreabout Prevalence of Secondary Immunotherapeutic Targets in the Absence of Established Immune Biomarkers in Solid Tumors
Poster - 10 November 2021 Novel Immunotherapeutic Targets in Cancer of Unknown Primary (CUP) Read Moreabout Novel Immunotherapeutic Targets in Cancer of Unknown Primary (CUP)
Poster - 22 June 2020 Anti-mPD-1 Reduces the Immuno-Suppressive Phenotype of Myeloid Subsets in the Murine Hepa 1-6 Tumor Read Moreabout Anti-mPD-1 Reduces the Immuno-Suppressive Phenotype of Myeloid Subsets in the Murine Hepa 1-6 Tumor
Poster - 22 June 2020 Immunophenotypic and Transcriptome Analyses of CT26 and 4T1-Luc Tumor Models Following Anti-mCTLA-4 Treatment Read Moreabout Immunophenotypic and Transcriptome Analyses of CT26 and 4T1-Luc Tumor Models Following Anti-mCTLA-4 Treatment
Poster - 22 June 2020 Combined Focal Radiation and Immune Checkpoint Inhibition Enhances Anti-Tumor Responses over Single Agent Treatment in a Murine Mammary Carcinoma Model Read Moreabout Combined Focal Radiation and Immune Checkpoint Inhibition Enhances Anti-Tumor Responses over Single Agent Treatment in a Murine Mammary Carcinoma Model
Poster - 22 June 2020 Targeted Radiation in Combination With Immunotherapy Agents in Murine Breast Cancer Models Read Moreabout Targeted Radiation in Combination With Immunotherapy Agents in Murine Breast Cancer Models
Poster - 22 June 2020 Gene Expression Profiling, Digital Spatial Profiling and Multiplex Immunohistochemistry of the Tumor-Immune Microenvironment in HNSCC Tumors Read Moreabout Gene Expression Profiling, Digital Spatial Profiling and Multiplex Immunohistochemistry of the Tumor-Immune Microenvironment in HNSCC Tumors
Poster - 22 June 2020 Characterization of the Orthotopic MMTV-PyMT Murine Mammary Carcinoma Model Following Radiation and Immune Checkpoint Blockade Read Moreabout Characterization of the Orthotopic MMTV-PyMT Murine Mammary Carcinoma Model Following Radiation and Immune Checkpoint Blockade
Poster - 22 June 2020 Development of a Robust MGMT Promoter Methylation Assay for Glioblastoma Multiforme Read Moreabout Development of a Robust MGMT Promoter Methylation Assay for Glioblastoma Multiforme
Poster - 13 April 2019 Systemic and Subcutaneous Modeling of A20 Murine B Cell Lymphoma in Mice: A Comparative Assessment Read Moreabout Systemic and Subcutaneous Modeling of A20 Murine B Cell Lymphoma in Mice: A Comparative Assessment
Poster - 10 April 2019 Radiation Response in Preclinical Orthotopic Models of Brain Cancer Read Moreabout Radiation Response in Preclinical Orthotopic Models of Brain Cancer
Poster - 3 April 2019 Preclinical Use of Focal Radiation and Immune Checkpoint Blockade to Improve Therapeutic Response in an Immunologically Cold Tumor Read Moreabout Preclinical Use of Focal Radiation and Immune Checkpoint Blockade to Improve Therapeutic Response in an Immunologically Cold Tumor
Poster - 3 April 2019 ID8-Luc Syngeneic Ovarian Cancer Model for Preclinical Evaluation of Immunomodulatory Molecules Read Moreabout ID8-Luc Syngeneic Ovarian Cancer Model for Preclinical Evaluation of Immunomodulatory Molecules
Poster - 18 April 2018 High-Throughput Analysis of MAPK and JAK-STAT Signaling in CT26 Tumors Using a Combination of Immunophenotyping and Phospho-Flow Cytometry Read Moreabout High-Throughput Analysis of MAPK and JAK-STAT Signaling in CT26 Tumors Using a Combination of Immunophenotyping and Phospho-Flow Cytometry
Poster - 18 April 2018 Evaluation of Immunomodulatory Agents in Classically Immunologically "Cold" Cancers Using Syngeneic Mouse Models of Breast and Ovarian Cancer Read Moreabout Evaluation of Immunomodulatory Agents in Classically Immunologically "Cold" Cancers Using Syngeneic Mouse Models of Breast and Ovarian Cancer
Poster - 18 April 2018 Radiation Enhances Anti-Tumor Activity of Checkpoint Blockade in Syngeneic Tumor Models Read Moreabout Radiation Enhances Anti-Tumor Activity of Checkpoint Blockade in Syngeneic Tumor Models
Poster - 14 April 2018 Unmasking T Cell Heterogeneity via Single Cell Transcriptomic Profiling Read Moreabout Unmasking T Cell Heterogeneity via Single Cell Transcriptomic Profiling
Poster - 30 October 2017 Sensitivity of Syngeneic Tumor Models to Focal Radiation Read Moreabout Sensitivity of Syngeneic Tumor Models to Focal Radiation
Poster - 9 May 2017 Preclinical Models of Multiple Myeloma Read Moreabout Preclinical Models of Multiple Myeloma
Poster - 5 April 2017 Focal Radiation Enhances Paclitaxel Therapy in a Mouse Model of Triple Negative Breast Cancer Read Moreabout Focal Radiation Enhances Paclitaxel Therapy in a Mouse Model of Triple Negative Breast Cancer
Poster - 5 April 2017 Image-Guided Focal Irradiation in Syngeneic Preclinical Oncology Mouse Models Read Moreabout Image-Guided Focal Irradiation in Syngeneic Preclinical Oncology Mouse Models
Poster - 20 April 2016 Preclinical Assessment of Anti-Tumor Activity and Immune Response in Syngeneic Tumor Models Read Moreabout Preclinical Assessment of Anti-Tumor Activity and Immune Response in Syngeneic Tumor Models
Poster - 20 April 2016 In-Depth Myeloid Cell Characterization in the Murine Syngeneic CT.26 Colon Carcinoma Model by 10-Color Flow Cytometry Read Moreabout In-Depth Myeloid Cell Characterization in the Murine Syngeneic CT.26 Colon Carcinoma Model by 10-Color Flow Cytometry
Poster - 8 November 2015 Preclinical Response of Murine Syngeneic Tumor Models to Immune Checkpoint Inhibitor Antibodies Read Moreabout Preclinical Response of Murine Syngeneic Tumor Models to Immune Checkpoint Inhibitor Antibodies
Info Sheet - 14 June 2024 Liquid biopsy regulatory considerations, current utility, and future directions
Info Sheet - 14 June 2024 Early ctDNA molecular response enhanced through integrated analyses of cell-free DNA and matched white blood cells
Info Sheet - 27 September 2023 Comprehensive laboratory testing for adoptive cell therapies: Supporting preclinical and clinical testing to advance your precision medicine initiative
Info Sheet - 27 September 2023 Advance Your Cell and Gene Therapies With Scientific Insights Across Every Stage of Development
Info Sheet - 3 June 2022 Harnessing the Power of Real-World Data to Drive More Effective Decision Making in Oncology Clinical Trials
Info Sheet - 1 February 2021 Covance by Labcorp and Tempus Accelerate Recruitment of Hard-to-Find Patients
Article - 21 December 2023 Customizing solutions for RNA-based therapeutics Read Moreabout Customizing solutions for RNA-based therapeutics
Article - 13 December 2023 Empowering development and enabling seamless assay transfer Read Moreabout Empowering development and enabling seamless assay transfer
Article - 13 December 2023 Driving efficient immuno-oncology drug development with optimal preclinical model selection Read Moreabout Driving efficient immuno-oncology drug development with optimal preclinical model selection
Article - 13 December 2023 Single-cell DNA sequencing technology Read Moreabout Single-cell DNA sequencing technology
Article - 7 December 2023 OmniSeq INSIGHT: Using immune profiling to stratify head and neck cancer subjects in an immunotherapy clinical trial Read Moreabout OmniSeq INSIGHT: Using immune profiling to stratify head and neck cancer subjects in an immunotherapy clinical trial
Article - 28 September 2023 Cell therapy for treatment of cancer Read Moreabout Cell therapy for treatment of cancer
Article - 5 July 2023 An introduction to chimeric antigen receptor-natural killer (CAR-NK) cell therapy Read Moreabout An introduction to chimeric antigen receptor-natural killer (CAR-NK) cell therapy
Article - 5 July 2023 Oncology CAR T-Cell Therapy: Preclinical Model Development and Adaptive Clinical Design Lead to Successful US/EU Registration Read Moreabout Oncology CAR T-Cell Therapy: Preclinical Model Development and Adaptive Clinical Design Lead to Successful US/EU Registration
Article - 20 October 2022 How Labcorp Mobile Clinical Services may improve the patient experience in oncology studies Read Moreabout How Labcorp Mobile Clinical Services may improve the patient experience in oncology studies
Article - 15 August 2022 Realizing the potential of decentralized clinical trials in oncology Read Moreabout Realizing the potential of decentralized clinical trials in oncology
Article - 30 June 2022 Working Urgently to Enroll a Patient in a Cancer Trial During the Pandemic Read Moreabout Working Urgently to Enroll a Patient in a Cancer Trial During the Pandemic
Article - 11 February 2022 Aligning Core Values to Advance an Oncology Program Read Moreabout Aligning Core Values to Advance an Oncology Program
Article - 22 June 2021 Applying Expertise to Support Biomarker Discovery and Development Case Study Read Moreabout Applying Expertise to Support Biomarker Discovery and Development Case Study
Article - 7 May 2021 Development, Commercialization and Utilization of Companion Diagnostics White Paper Read Moreabout Development, Commercialization and Utilization of Companion Diagnostics White Paper
Article - 26 February 2021 From Biomarkers to Companion Diagnostics: Transforming the Therapeutic Landscape of Non-Small Cell Lung Cancer Case Study Read Moreabout From Biomarkers to Companion Diagnostics: Transforming the Therapeutic Landscape of Non-Small Cell Lung Cancer Case Study
Article - 25 February 2021 The Evolving Precision Medicine Landscape and Therapeutic Options in Breast Cancer Case Study Read Moreabout The Evolving Precision Medicine Landscape and Therapeutic Options in Breast Cancer Case Study
Article - 20 November 2017 Addressing Immunotherapy Drug Development Challenges: An Evidence-Based Approach Read Moreabout Addressing Immunotherapy Drug Development Challenges: An Evidence-Based Approach
Article - 12 October 2017 Providing Flexibility in Oncology Early Clinical Development Read Moreabout Providing Flexibility in Oncology Early Clinical Development
Article - 19 July 2017 Finding Your Target: Biomarker-Guided Adaptive Trial Design in Immuno-oncology Read Moreabout Finding Your Target: Biomarker-Guided Adaptive Trial Design in Immuno-oncology
Article - 6 June 2017 How to Maximize Patient Recruitment in Oncology Trials Read Moreabout How to Maximize Patient Recruitment in Oncology Trials
Article - 10 September 2016 Manage Complexity. Exceed Expectations. Clinical Oncology Success Case Study Read Moreabout Manage Complexity. Exceed Expectations. Clinical Oncology Success Case Study
Article - 10 June 2015 Adaptive Trial Designs: Improving the Efficiency of Drug Development Read Moreabout Adaptive Trial Designs: Improving the Efficiency of Drug Development