Neuroblastoma is the most prevalent solid tumor in childhood and the most common tumor in infants less than 1 year of age. In spite of aggressive multi-modal therapeutic approaches, the five-year survival rate in patients with high-risk neuroblastoma premains poor at less than 50%.

AACR 2017 -- Use of image-guided focal irradiation is a mainstay of human cancer treatment. Image guidance allows for highly conformal treatment plans that minimize normal tissue toxicity and systemic response.

AACR 2017 -- Triple negative breast cancer (TNBC) accounts for 15-20% of all breast cancers in the United States. Patients with TNBC have poorer prognosis and therapeutic intervention is more challenging due to insensitivity to hormonal and anti-HER2 therapies. Therapeutic options for TNBC can include chemotherapy and/or radiation (RT) treatment.

AACR Hematologic Malignancies Conference 2017 -- Multiple myeloma is a clonal B cell malignancy characterized by the accumulation of terminally differentiated, antibody-producing plasma cells in the bone marrow that is invasive and drug resistant. Patients are generally asymptomatic until very late state disease.