Going Virtual: Evolving Real-World Evidence Study Design

Site-based observational research has many challenges. Considerable time and cost is invested in identifying suitable sites and investigators, and then managing them to ensure recruitment and research are conducted in line with the protocol and local review board requirements. Furthermore, there is considerable burden to subjects - they may have to travel a distance to research sites to attend lengthy appointments, resulting in out-of-pocket expenses, lost time and inconvenience.