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Expected Turnaround Time
3 - 5 days
Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Related Documents
Specimen Requirements
Specimen
Serum and cerebrospinal fluid (CSF)
Volume
1.5 mL serum and 1 mL CSF
Minimum Volume
0.7 mL serum and 0.5 mL CSF
Container
Red-top tube or gel-barrier tube and sterile container for CSF
Storage Instructions
Room temperature
Stability Requirements
Temperature | Period |
|---|---|
Room temperature | 14 days |
Refrigerated | 14 days |
Frozen | 6 months |
Freeze/thaw cycles | Stable x2 |
Test Details
Limitations
Conditions in which lymphoreticular elements of the CNS produce immunoglobulins will result in false-positive (in relation to multiple sclerosis) elevations. Such conditions include (but are not limited to) aseptic meningitis, lymphoma, neurosyphilis, Guillain-Barré syndrome, and cerebral lupus erythematosus. These conditions, however, are either uncommon or are not frequently associated with an increased IgG index.
Methodology
CSF IgG, CSF albumin and serum IgG: Immunologic; serum albumin: spectrophotometry; ratio, index and synthesis rate by calculation
LOINC® Map
| Order Code | Order Code Name | Order Loinc | Result Code | Result Code Name | UofM | Result LOINC |
|---|---|---|---|---|---|---|
| 203836 | IgG Index+Synthesis Rate | 012212 | IgG, Quant, CSF | mg/dL | 2464-6 | |
| 203836 | IgG Index+Synthesis Rate | 012230 | Albumin, CSF | mg/dL | 1746-7 | |
| 203836 | IgG Index+Synthesis Rate | 001776 | Immunoglobulin G, Qn, Serum | mg/dL | 2465-3 | |
| 203836 | IgG Index+Synthesis Rate | 001081 | Albumin | g/dL | 1751-7 | |
| 203836 | IgG Index+Synthesis Rate | 160311 | IgG/Alb Ratio, CSF | 2470-3 | ||
| 203836 | IgG Index+Synthesis Rate | 101124 | CSF IgG Index | 14117-6 | ||
| 203836 | IgG Index+Synthesis Rate | 085937 | IgG, Syn Rate,CSF | mg/day | 14116-8 | |
| 203836 | IgG Index+Synthesis Rate | 120173 | CSF/Serum Alb. Index | 1756-6 |
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CPT Statement/Profile Statement
The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf